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What other drugs will affect Ritalin (methylphenidate)?

Do not take ritalin (methylphenidate) if you have taken a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.

Before taking ritalin (methylphenidate), tell your doctor if you are taking any of the following medicines:

  • warfarin (Coumadin).
  • phenytoin (Dilantin).
  • phenobarbital (Luminal, Solfoton).
  • primidone (Mysoline).
  • a tricyclic antidepressant such as nortriptyline (Pamelor), amitriptyline (Elavil, Endep), doxepin (Sinequan), desipramine (Norpramin), clomipramine (Anafranil), or imipramine (Tofranil).
  • a selective serotonin reuptake inhibitor such as fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft).
  • clonidine (Catapres).
  • guanethidine (Ismelin).

You may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with ritalin (methylphenidate). Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.