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Daytrana Side Effects

By Dr. Emily Kensington

Common Daytrana side effects include decreased appetite, irritability, and insomnia. Daytrana is a stimulant medication used to treat Attention Deficit Hyperactivity Disorder, also referred to as ADD or ADHD.

It works by interacting with the chemicals in the brain that contribute to impulse control and hyperactivity, which are the more challenging symptoms of the condition.

Daytrana differs from other ADHD medications in that it is delivered via a skin patch, not tablets or pills.

Decreased Appetite

This is a common side effect of all stimulants. If it continues to be problematic, dosages and medication times can be adjusted. Often a large breakfast, small lunch and large supper can do the trick. Or a late evening snack can also help.


Rebound is the phenomenon where some experience irritability or depression for an hour as the drug wears off. One can avoid rebound by spacing the doses closer together, giving a smaller dose after the final larger dose, or by switching to a longer acting stimulant.

Recently several new long-acting stimulant preparations have been released. Although the long-acting compounds often have less rebound, it may still occur in susceptible individuals.

"The Jitters"

Ever consumed too much caffeine? Like all stimulants, Daytrana produces the jitters and the shakes. To avoid this try eliminating all caffeine and other stimulants.

A small dose of a beta-blocker (a type of blood pressure medication) can block tremors, shakes and jitters. Be sure to eat regular meals and ingest some food.

Upset Stomach

Another common side effect of any stimulant. Take the medication with meals or eat smaller, more frequent meals.

Sleep Disturbances

Sometimes sleep disturbances are due to ADHD, not the medication. Therefore, it is a good idea to take a sleep history before starting taking any stimulants.

If sleep disturbances are due to the medication, there are several options such as adjusting dosages and medication times.


Irritability may be due to ADHD but if it is due to the medication the dosage may be altered or another ADHD medication could be substituted.

Bottom Line

It is important to remember that all medications have side effects, both positive and negative, and this one is no different.

If you experience any serious negative Daytrana side effects, seek medical attention and report the symptoms to your prescribing doctor immediately.

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